IMUREGEN Nucleotides Supplement Review
IMUREGEN is owned and manufactured by UniRegen from the Czech Republic. It was invented by a Pharmacist from Prague. Immunologists Dr. D. Rakus in the 1930s. Dr. Rakús together with Dr. B. Dolezal did several experiments, mostly done in their homes. Eventually, the release of the first commercially available supplement – Juvenil, was followed by more advanced ingredients produced by enzymatic disintegration of beef blood which was sold under competing and various names such as Juwi, Juwík, Animex, Servisin, Fortisin, Preventan, and Fromin (Imuregen).
→ Imuregen clinical study
After the death of Dr. Rakús, Bedřich Doležel continued his quest and development of the product, which was then called differently. The rights to sell the product was first given to a company called Jednota Hronov. Then it was sold to a small family run business that sold feed products. In 1995, UNIREGEN Ltd. was established and reintroduced the rebranded product called IMUREGEN. The Health Care Ministry approved the product in 1998.
The company UniRegen that produces IMUREGEN, also competitors that produce their own nucleotide supplement like the brand Retisin, Lyastin, Ovosan. IMUREGEN was marketed in the US years ago but was unsuccessful. In 2014, the franchise was given to a company in the Philippines, Forever Healthy Products, Inc. (FHP) and in 2018, IMUREGEN was redistributed and sold in the USA.
UNIREGEN SPOL. S R.O.
Na Brzdách 72, 547 01 Náchod, Czech Republic
Phone: +420 491 428 124
IMUREGEN Capsule and Liquid claim several health benefits through its complex dietary nucleotides, peptides, essential amino acids, vitamins, and minerals. Since it is sold through Multi-Level Marketing, there are several resellers that propagate amazing claims such as “healing abilities in the DNA level.” Their powerful marketing strategy is helping the product gain attention worldwide, but can IMUREGEN make such claims?
IMUREGEN is advertised as a supplement for the prevention of cardiovascular diseases, diabetics, asthma, cancer. It also claims it can protect against bacterial and viral infections with antiseptic effect, acting on the endocrine glands, the regulator energy system. Other claims include regulating the immunoregulatory functions which affect memory improvement, mobility, employability, progress allergies, wound healing, and liver function. (Source: Sysyfos, Zpravodaj 2006)
Contents, Ingredients, and Use
IMUREGEN contains amino acids, minerals, salts, vitamins, and iron. It is made through an
Product Variation: Caplet and Liquid
A nucleotide is a simple and common substance we can eat every day. It contains amino acids, minerals and salts, vitamins, and iron that is found in beef meat proteins or even caviar. (Petr Sima co-author of IMUREGEN final report)
Preparation or Dosage
The general dosage recommended for children and adults is from 1 caplet to as much as 15 caplets per day for patients with diseases. For therapeutic care, children are to be given at least 3 caplets or 1 tsp. of IMUREGEN in liquid form.
Years in the market
IMUREGEN labeled as Juvenil was introduced in the 1950s, later it was modified when development in the extraction and use of bovine blood extracts were improved. Actual data is not available in the manufacturer’s official website on how the product evolved from the 1950s. It would be safe to assume that the product has been around for more than 20 years, mainly distributed in the Czech Republic and in Europe.
How the product is sold & distributed
IMUREGEN Capsule and Liquid are sold as retail online in its native Czech Republic. It was introduced in the USA in 2010 and sold in online health stores labeled as ‘ReGen’. The unsuccessful venture between the owners and the USA counterpart paved the way for a new global distributor for the product. In March 2016, Forever Healthy Product (FHP), a company based in the Philippines was given the rights to sell the product by using the Multi-Level Marketing or MLM sales model.
CLAIMS AND BENEFITS
During the nuclear leak in Chernobyl, many became fatally ill because of radiation exposure. Patients had “unhealable” burns and wounds. IMUREGEN was given to some of the patients and was said to have recovered, after taking this brand of nucleotides supplement. Nucleotides that comes in several brands (like IMUREGEN) has the following benefits:
Nucleotides have important effects on the growth and development of cells which have a rapid turnover, such as those in the immune system and the gastrointestinal tract. Dietary nucleotide improves markers of the immune response to strenuous exercise in a cold environment. Nucleotides help gut mucosal defense, which is also part of the immune system.
Nucleotides enhance intestinal repair after injury (alcohol, gluten, casein, among others). Dietary nucleotides enhance the intestinal absorption of iron. They have been found to promotes healing of small bowel ulcers in experimental ulcerative ileitis. They also help in the prevention and treatment of the injurious effects of NSAIDs (aspirin, ibuprofen)
In rats, dietary nucleotides increase phosphatidylcholine, phosphatidylethanolamine, DHA and arachidonic acid in the cerebral cortex. These rats were found to have enhanced learning. Nucleotides supplementation is recommended for children with malnutrition.
Irritable Bowel Syndrome
Irritable Bowel Syndrome (IBS) is a chronic disorder affecting an estimated 15 – 22% of western populations. Animal work shows that villi height and crypt depth in the intestine is increased as a result of dietary nucleotides. Dietary nucleotide supplementation improves some of the symptoms of irritable bowel above the baseline and placebo level. A similar effect is seen in aiding IBS through Laminine supplement.
→ Imuregen ImunPLUS Review
The gastrointestinal tract epithelium plays an important role not only in digestion and absorption of nutrients but also in antigen and pathogen signal translocation toward the gut-associated lymphoid tissue. Malnutrition in various degrees is recognized as the most common cause of the immune system dysfunction. Research done in the past several years has revealed that dietary nucleotides (dNT) represent an essential compound of nutrition because of their importance in metabolic pathways, energetic processes, and nucleic acid synthesis during tissue renewal.
Much evidence accumulated suggests that dNT are essential for the growth and maturation of the gut epithelia. In previous experiments, we have documented immunoregulative properties of dNT-containing extracts. In this study, Balb/c female mice were fed (1) standard diet, (2) dNT-supplemented diet, and (3) dNT-supplemented water for 4 weeks. The supplement in a dose of 100 mg/kg/l comprised the original extract (Imuregen, Uniregen Ltd., Náchod, Czech Republic).
The highest growth of intestinal villi was observed in the group administered dNT-supplemented water. We have found no pathological changes of intestinal epithelium in any experimental group.
REBUTTAL ON THESE CLAIMS & BENEFITS
The claims of IMUREGEN to regenerate the villi appear to be valid. When a sick person has a gut failure, it will be difficult to administer nutritional supplements or even medicine to help the body recover. Thus, people with “broken gut” eventually dies. Taking probiotics or protein dietary supplements like IMUREGEN is beneficial.
Imuregen would not be unique in accomplishing this task as there are other supplements that can replicate the effect.
Working on DNA level is overemphasized
RNA (ribonucleic acid) and DNA (deoxyribonucleic acid) are chemicals called nucleotides that are made by the body. They appear to be essential under conditions of rapid growth such as important effects on the growth and development of cells which have a rapid turnover such as those in the immune system and the gastrointestinal tract.
Our body makes nucleotide and taking this supplement is another way to replace a meat diet. All protein dietary supplements work well in and from within DNA level. IMUREGEN is not an exception, but a brand from many other brands of nucleotides available over the counter.
Side effects of overdosing nucleotides supplement
Our body always makes nucleotides. They are components of DNA and RNA and starving the body reduces the nucleotides our body makes. Likewise, too much nucleotides can negatively affect the pituitary glands resulting in unintended side effects.
IMUREGEN that comes from beef blood has the nature of iodine. The pituitary glands can become overexcited, overdosing is not recommended.
Nucleotide supplements can come from yeast or animal ingredients that are high in purine. Individuals taking too much is at risk of gout. Taking nucleic acids increases your dietary intake of uric acid said Dr. Ed Blonz.
IMUREGEN is a simple nucleotide intended to be the bearer of action, as well as protein fractions. Its ingredients that comprise of bovine (beef) blood, the peptides and amino acids, sugars, fats, minerals extracted from it are beneficial, but so is eating meat-rich in nucleotides or any other amino-based dietary supplements. Their buzzword “DNA” is overemphasized and used in their marketing materials, insinuating cure for nearly all types of body anomalies or fix gene-related dysfunctions – no dietary supplement can do that.
Alternative Nucleotide Supplements
Nucleotides are simple proteins that are available in other brands and with equal nutritional benefits. Any protein supplements (either coming from beef blood, egg extracts, or others) have amino acid and all work on DNA/RNA level. IMUREGEN is a legitimate healthy product but some of its claims are exaggerated.